Promoting lumbar spinal fusion by adenovirus-mediated bone morphogenetic protein-4 gene therapy.

Abstract

OBJECTIVE To determine whether an adenoviral construct containing bone morphogenetic protein-4 (BMP-4) gene can be used for lumbar spinal fusion. METHODS Twelve New Zealand white rabbits were randomly divided into two groups, 8 in the experimental group and 4 in the control group. Recombinant, replication-defective type 5 adenovirus with the… (More)

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Cite this paper

@article{Zhao2007PromotingLS, title={Promoting lumbar spinal fusion by adenovirus-mediated bone morphogenetic protein-4 gene therapy.}, author={Jian Zhao and Dun-yan Zhao and Aiguo Shen and Fan Liu and Feng Zhang and Yu Sun and Hong-fu Wu and Chun-feng Lu and Hong-guang Shi}, journal={Chinese journal of traumatology = Zhonghua chuang shang za zhi}, year={2007}, volume={10 2}, pages={72-6} }