Promoting longevity by maintaining metabolic and proliferative homeostasis.

  title={Promoting longevity by maintaining metabolic and proliferative homeostasis.},
  author={Lifen Wang and Jason Karpac and Heinrich Jasper},
  journal={The Journal of experimental biology},
  volume={217 Pt 1},
Aging is characterized by a widespread loss of homeostasis in biological systems. An important part of this decline is caused by age-related deregulation of regulatory processes that coordinate cellular responses to changing environmental conditions, maintaining cell and tissue function. Studies in genetically accessible model organisms have made significant progress in elucidating the function of such regulatory processes and the consequences of their deregulation for tissue function and… CONTINUE READING
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