Promoting abstinence from cocaine and heroin with a methadone dose increase and a novel contingency.

@article{Epstein2009PromotingAF,
  title={Promoting abstinence from cocaine and heroin with a methadone dose increase and a novel contingency.},
  author={David H. Epstein and John Schmittner and Annie Umbricht and J. R. Schroeder and Eric T Moolchan and Kenzie L Preston},
  journal={Drug and alcohol dependence},
  year={2009},
  volume={101 1-2},
  pages={92-100}
}
To test whether a combination of contingency management and methadone dose increase would promote abstinence from heroin and cocaine, we conducted a randomized controlled trial using a 2 x 3 (dosexcontingency) factorial design in which dose assignment was double-blind. Participants were 252 heroin- and cocaine-abusing outpatients on methadone maintenance. They were randomly assigned to methadone dose (70 or 100mg/day, double-blind) and voucher condition (noncontingent, contingent on cocaine… CONTINUE READING

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