Promoter methylation of MGMT gene in serum of patients with esophageal squamous cell carcinoma in North East India.

Abstract

BACKGROUND Promoter hypermethylation is a common event in human cancer. O6-methylguanine-DNA methyltransferase (MGMT) is a gene involved in DNA repair, which is methylated in a variety of cancers. We aimed to explore the methylation status of MGMT gene among the North Eastern population where esophageal cancer incidence and exposure to carcinogens like… (More)

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