Promoter hypomethylation regulates CD133 expression in human gliomas

Abstract

Brain tumor-initiating cells (BTICs) have been enriched using antibodies against the cell surface protein CD133; however, the biological relevance and the regulatory mechanism of CD133 expression in human gliomas are not yet understood. In this study, we initially demonstrated that CD133 was overexpressed in high-grade human glioblastomas where CD133… (More)
DOI: 10.1038/cr.2008.270

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@article{Tabu2008PromoterHR, title={Promoter hypomethylation regulates CD133 expression in human gliomas}, author={Kouichi Tabu and Ken Sasai and Taichi Kimura and Lei Wang and Eiko Aoyanagi and Shinji Kohsaka and Mishie Ann Tanino and Hiroshi Nishihara and Shinya Tanaka}, journal={Cell Research}, year={2008}, volume={18}, pages={1037-1046} }