Promoter hypermethylation and expression of sprouty 2 in endometrial carcinoma.

Abstract

Sprouty 2 is a key antagonist regulator of receptor tyrosine kinases, and downstream signaling pathways, like fibroblastic growth factor (FGF) and Ras-mitogen-activated protein kinase (RAS-MAPK). By controlling these pathways, sprouty 2 is involved in regulation of cell proliferation, differentiation, and angiogenesis. Alterations in fibroblastic growth… (More)
DOI: 10.1016/j.humpath.2010.08.001

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Cite this paper

@article{Velasco2011PromoterHA, title={Promoter hypermethylation and expression of sprouty 2 in endometrial carcinoma.}, author={A. Sanz - Velasco and Judit Pallar{\'e}s and Maria Forns i Santacana and S{\'o}nia Gatius and Melisa Fernandez and M. Teresa Domingo and Joan Valls and Andr{\'e}e Yeramian and Mario Encinas and Xavier Dolcet and Xavier Mat{\'i}as-Guiu}, journal={Human pathology}, year={2011}, volume={42 2}, pages={185-93} }