Promoter activity of the sea urchin (Paracentrotus lividus) nucleosomal H3 and H2A and linker H1 α-histone genes is modulated by enhancer and chromatin insulator

@inproceedings{Cavalieri2009PromoterAO,
  title={Promoter activity of the sea urchin (Paracentrotus lividus) nucleosomal H3 and H2A and linker H1 α-histone genes is modulated by enhancer and chromatin insulator},
  author={Vincenzo Cavalieri and Raffaella Melfi and Giovanni Spinelli},
  booktitle={Nucleic acids research},
  year={2009}
}
Core promoters and chromatin insulators are key regulatory elements that may direct a transcriptional enhancer to prefer a specific promoter in complex genetic loci. Enhancer and insulator flank the sea urchin (Paracentrotus lividus) alpha-histone H2A transcription unit in a tandem repeated cluster containing the five histone genes. This article deals with the specificity of interaction between the H2A enhancer-bound MBF-1 activator and histone gene promoters, and with the mechanism that leads… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Identification of the enhancer binding protein MBF-1 of the sea urchin modulator alpha-H2A histone gene

  • C. Alessandro, P. Di Simone, A. Buscaino, L. Anello, F. Palla, G. Spinelli
  • Biochem. Biophys. Res. Commun.,
  • 2002
Highly Influential
6 Excerpts

Down-regulation of early sea urchin histone H2A gene relies on cis regulative sequences located in the 5’ and 3’ regions and including the enhancer blocker sns

  • D. Di Caro, R. Melfi, +5 authors G. Spinelli
  • J. Mol. Biol.,
  • 2004
Highly Influential
6 Excerpts

Functional characterization of the enhancer blocking element of the sea urchin early histone gene cluster reveals insulator properties and three essential cis-acting sequences

  • R. Melfi, F. Palla, +4 authors G. Spinelli
  • J. Mol. Biol.,
  • 2000
Highly Influential
5 Excerpts