Promising use of minocycline augmentation with clozapine in treatment-resistant schizophrenia.

Abstract

Treatment-resistant schizophrenia is a major health problem in the UK with the majority of patients treated with clozapine. In up to 70% of cases there is only a partial response to clozapine with continuing refractory symptoms. We describe two cases in a UK mental health service where minocycline was found to be useful and well tolerated as an augmentation agent with clozapine in the improvement of previously resistant positive and negative symptoms.

DOI: 10.1177/0269881114527358

Cite this paper

@article{Qurashi2014PromisingUO, title={Promising use of minocycline augmentation with clozapine in treatment-resistant schizophrenia.}, author={Inti Qurashi and Jana D Collins and Imran Bashir Chaudhry and Nusrat Husain}, journal={Journal of psychopharmacology}, year={2014}, volume={28 7}, pages={707-8} }