Prominent neuronal-specific tub gene expression in cellular targets of tubby mice mutation.

@article{Sahly1998ProminentNT,
  title={Prominent neuronal-specific tub gene expression in cellular targets of tubby mice mutation.},
  author={Iman Sahly and Kar{\"i}n Gogat and Alexandra Kobetz and Dominique Marchant and Maurice M{\'e}nasche and Mona Castel and Fr{\'e}d{\'e}ric Revah and J L Dufier and Mich{\'e}le Guerre-Millo and Marc M. Abitbol},
  journal={Human molecular genetics},
  year={1998},
  volume={7 9},
  pages={1437-47}
}
The tubby strain of mice exhibits maturity-onset obesity and sensory deficits in vision and hearing. The mutated gene, tub , responsible for this phenotype was identified recently, but the function of the TUB protein has not been deduced from its amino acid sequence. This prompted us to undertake expression mapping studies with the hope that they might help to elucidate the biological role of the TUB protein. We report the tub gene expression pattern in embryonic, fetal and adult mice tissues… CONTINUE READING
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