Prolyl hydroxylase-2 inhibits liver tumor cell proliferation and cyclin D1 expression in a hydroxylase-dependent manner.

@article{Tao2016ProlylHI,
  title={Prolyl hydroxylase-2 inhibits liver tumor cell proliferation and cyclin D1 expression in a hydroxylase-dependent manner.},
  author={Yifeng Tao and Feng Lin and Ruidong Li and Jie Shen and Zhengxin Wang},
  journal={The international journal of biochemistry & cell biology},
  year={2016},
  volume={77 Pt A},
  pages={129-140}
}
Prolyl hydroxylase 2 is a key regulator of hypoxia-inducible factor 1 alpha protein, and has previously been implicated as a tumor suppressor in various cancers. However, the function of prolyl hydroxylase 2 in liver cancer has yet to be elucidated. Characterization of prolyl hydroxylase 2 function and related mechanisms in liver cancer may enable the… CONTINUE READING