Prolyl Endopeptidase Is Involved in Cellular Signalling in Human Neuroblastoma SH-SY5Y Cells

@article{MorenoBaylach2011ProlylEI,
  title={Prolyl Endopeptidase Is Involved in Cellular Signalling in Human Neuroblastoma SH-SY5Y Cells},
  author={M. J. Moreno-Baylach and K. Puttonen and J. Tenorio-Laranga and J. Ven{\"a}l{\"a}inen and M. Storvik and M. Forsberg and J. A. Garc{\'i}a-Horsman},
  journal={Neurosignals},
  year={2011},
  volume={19},
  pages={97 - 109}
}
Prolyl endopeptidase (PREP), probably acting through the inositol cycle, has been implicated in memory and learning. However, the physiological role of PREP is unknown. It has been shown that PREP expression, regulated in cerebellar granule cells, has probably a role in cell proliferation and differentiation. Here, we report the levels and subcellular distribution of PREP in human neuroblastoma SH-SY5Y cells in proliferating conditions and under differentiation induced by retinoic acid (RA). We… Expand
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