• Medicine
  • Published 2001

Prolonged xenograft survival by leflunomide in mouse-to-rat cardiac xenograft model

@inproceedings{Zhenxian2001ProlongedXS,
  title={Prolonged xenograft survival by leflunomide in mouse-to-rat cardiac xenograft model},
  author={Yao Zhen-xian},
  year={2001}
}
ObjectiveTo observe the role of leflunomide (Lef) in mouse to rat heart transplantationmodel. Methods The animals were divided into 8 groups: group A (n=6) served as control and received no immunosuppression; group B (n=6) cyclosporine (CsA); group C (n=6), cyclophosphamide (CTX); group D (n=5) Lef; group E (n=5) CsA plus CTX; group F (n=5) Lef plus CsA; group G (n=6) Lef plus CTX; and groupH (n=5) Lef, CsA plus CTX. C3, IgG and CD68 were determined by using immunohistochemical method. Results… CONTINUE READING

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