Prolonged untreated illness duration from prodromal onset predicts outcome in first episode psychoses.

@article{Keshavan2003ProlongedUI,
  title={Prolonged untreated illness duration from prodromal onset predicts outcome in first episode psychoses.},
  author={Matcheri S. Keshavan and Gretchen L Haas and Jean M. Miewald and Debra M. Montrose and R. L. Raghunath Reddy and Nina Schooler and John A. Sweeney},
  journal={Schizophrenia bulletin},
  year={2003},
  volume={29 4},
  pages={
          757-69
        }
}
Several, although not all, studies suggest that prolonged duration of untreated illness (DUI) predicts poor outcome in psychotic disorders such as schizophrenia. It is unclear whether this association can be explained by factors such as baseline deficits or poor premorbid adjustment. First episode psychotic patients were evaluated at 1 and 2 years following baseline evaluations. Predictive measures showing significant correlations with outcome were entered in multiple regression analyses with… CONTINUE READING

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