Prolonged survival in mice with advanced tumors treated with syngeneic or allogeneic intra-bone marrow–bone marrow transplantation plus fetal thymus transplantation

@article{Hosaka2010ProlongedSI,
  title={Prolonged survival in mice with advanced tumors treated with syngeneic or allogeneic intra-bone marrow–bone marrow transplantation plus fetal thymus transplantation},
  author={Naoki Hosaka and Wenhao Cui and Yuming Zhang and Takashi Takaki and Muneo Inaba and Susumu Ikehara},
  journal={Cancer Immunology, Immunotherapy},
  year={2010},
  volume={59},
  pages={1121-1130}
}
Thymic function decreases in line with tumor progression in patients with cancer, resulting in immunodeficiency and a poor prognosis. In the present study, we attempted to restore thymic function by BALB/c (H-2d) syngeneic (Syn), or B6 (H-2b) allogeneic (Allo) bone marrow transplantation (BMT) using intra-bone marrow–bone marrow transplantation (IBM–BMT… CONTINUE READING