Prolonged survival in culture of preantral follicles from polycystic ovaries.

  title={Prolonged survival in culture of preantral follicles from polycystic ovaries.},
  author={Lisa J Webber and Sharron A Stubbs and Jaroslav Stark and Raul A Margara and Geoffrey H. Trew and Stuart Lavery and Kate Hardy and Stephen Franks},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={92 5},
CONTEXT In polycystic ovary syndrome (PCOS), an increased proportion of follicles leave the primordial (resting) pool and initiate growth. However, there is little evidence for a reduced reproductive life span (early menopause) in women with PCOS, suggesting that the dynamics of follicle growth, and of follicle loss by atresia, is altered in PCOS. OBJECTIVE The aim of this study was to investigate the possibility that loss of preantral follicles by atresia is reduced in PCOS, leading to… CONTINUE READING
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