Prolonged survival for melanoma patients with elevated IgM antibody to oncofetal antigen.

@article{Jones1981ProlongedSF,
  title={Prolonged survival for melanoma patients with elevated IgM antibody to oncofetal antigen.},
  author={P. C. T. Jones and Lan L. Sze and Peter Y Liu and Donald L. Morton and Reiko F. Irie},
  journal={Journal of the National Cancer Institute},
  year={1981},
  volume={66 2},
  pages={249-54}
}
Antibody directed against a cultured melanoma cell line known to express an oncofetal antigen was measured in sera obtained from patients with stage II melanomas. This study was undertaken to determine if an inhibiting or enhancing effect on tumor growth would be suggested by a positive or negative correlation of antibody levels with tumor recurrence or patient survival. A positive correlation with disease-free interval and survival was detected among patients who had high levels of the IgM… CONTINUE READING