Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium.

@article{Ferrari1992ProlongedPP,
  title={Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium.},
  author={Roberto Ferrari and Fabio di Lisa and Jan Willem de Jong and Claudio Ceconi and Evasio Pasini and Roberta Barbato and Roberta Menab{\`o} and Mario Barbieri and Elisabetta Cerbai and Alessandro Mugelli},
  journal={Journal of molecular and cellular cardiology},
  year={1992},
  volume={24 3},
  pages={219-32}
}
Recently it has been reported that prolonged treatment with propionyl-L-carnitine, a carnitine derivative, results in a positive inotropic effect. To gain further insight into its mode of action, we pre-treated 253 rabbits for up to 10 days with daily doses of 1 mmol/kg propionyl-L-carnitine or L-carnitine intraperitoneally, using saline-treated animals as… CONTINUE READING