Prolonged interval between fusion and activation impairs embryonic development by inducing chromosome scattering and nuclear aneuploidy in pig somatic cell nuclear transfer.

@article{You2010ProlongedIB,
  title={Prolonged interval between fusion and activation impairs embryonic development by inducing chromosome scattering and nuclear aneuploidy in pig somatic cell nuclear transfer.},
  author={Jinyoung You and Kilyoung Song and Eunsong Lee},
  journal={Reproduction, fertility, and development},
  year={2010},
  volume={22 6},
  pages={977-86}
}
The aim of the present study was to examine the effect of various intervals between electrofusion and activation (FA interval) on the nuclear remodelling and development of somatic cell nuclear transfer (SCNT) embryos in pigs. Reconstructed oocytes were activated at 0 (simultaneous fusion and activation; SFA), 1, 2 and 3 h (delayed activation) after electrofusion; these groups were designated as DA1, DA2 and DA3, respectively. When oocyte nuclear status was examined at 0.5, 1, 2 and 3 h after… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 44 references

In vitro development of porcine nuclear transfer embryos reconstructed by intracytoplasmic microinjection of cumulus cell nuclei into in vitro matured oocytes

  • H. Nagashima, T. Kurihara, +6 authors H. Murakami
  • J. Reprod. Dev
  • 2002
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