Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats

@article{Yamaguchi2000ProlongedIO,
  title={Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats},
  author={Masayoshi Yamaguchi and Hiroyuki Kakuda and Ying Hua Gao and Yoshinori Tsukamoto},
  journal={Journal of Bone and Mineral Metabolism},
  year={2000},
  volume={18},
  pages={71-76}
}
The effect of the prolonged intake of dietary vitamin K2 (menaquinone-7, MK-7) on bone loss in ovariectomized (OVX) rats was investigated. OVX rats were freely given experimental diets containing the fermented soybean (natto; including 9.4 μg MK-7/100 g diet) without or with supplemental MK-7 (containing 14.1 or 18.8 μg of MK-7 as total per 100 g diet) for 150 days. Feeding produced a significant elevation of MK-7 concentration in the serum of OVX rats. In this case, the femoral MK-4 content… CONTINUE READING

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References

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Showing 1-10 of 14 references

Effect of menaquinone-7 purified from the fermented soybean (natto) in the femoral metaphysis from rat femur (in Japanese)

T Sato, Y Isobe, Y Ehara, M Yamaguchi
Vitamins • 1996
View 4 Excerpts
Highly Influenced

Effect of vitamin K2 (menaquinone-7) on bone metabolism in the femoral-metaphyseal tissues of normal and skeletal-unloaded rats: enhancement with zinc.

Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie • 1996
View 3 Excerpts

Enhancement of mineralization of human osteoblasts by vitamin K2 (menaquinone)

Y Koshihara, K Hoshi, M Shiraki
J Clin Exp Med • 1992
View 2 Excerpts

Origin of the vitamin K-dependent bone protein found in plasma and its clearance by kidney and bone

PA Price, MK Willamson, MK Lothringer, JW Lothringer
J Biol Chem • 1981
View 1 Excerpt

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