Prolonged hypothermia in rat: a safety study using brain-selective and systemic treatments.

Abstract

Hypothermia is an effective neuroprotectant for cardiac arrest and perinatal ischemic injury. Hypothermia also improves outcome after traumatic brain injury and stroke. Although the ideal treatment parameters (duration, delay, and depth) are not fully delineated, prolonged cooling is usually more effective than shorter periods. There is the concern that… (More)
DOI: 10.1089/ther.2012.0005

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