Prolonged faecal excretion of poliovirus in a nurse with common variable hypogammaglobulinaemia.

@article{Misbah1991ProlongedFE,
  title={Prolonged faecal excretion of poliovirus in a nurse with common variable hypogammaglobulinaemia.},
  author={S A Misbah and Peter A Lawrence and John B. Kurtz and Helen M. Chapel},
  journal={Postgraduate medical journal},
  year={1991},
  volume={67 785},
  pages={301-3}
}
A nurse with common variable hypogammaglobulinaemia was found to excrete a non-vaccine strain type II poliovirus for almost a year following a bout of gastroenteritis. Attempts were made to halt intestinal carriage of the virus in view of the possible risk of spread to immunocompromised patients and the risk of paralytic poliomyelitis to the patient himself. Three doses of killed Salk vaccine failed to stimulate salivary anti-polio antibodies. Excretion of the virus ceased spontaneously just… CONTINUE READING