Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment

@inproceedings{Bourton2011ProlongedEO,
  title={Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment},
  author={Emma C. Bourton and Piers Nicholas Plowman and Daniel Smith and Colin F Arlett and Christopher N. Parris},
  booktitle={International journal of cancer},
  year={2011}
}
The normal tissue tolerance levels to fractionated radiotherapy have been appreciated by a century of careful clinical observations and radiobiological studies in animals. During clinical fractionated radiotherapy, these normal tissue tolerance levels are respected, and severe sequelae of radiotherapy are avoided in the majority of patients. Notwithstanding, a minority of patients experience unexpectedly severe normal tissue reactions. The ability to predict which patients might form this… CONTINUE READING
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  • Sprung CN Cempaka NL Chao M McKay MJ. H2AX phosphorylatio Vasireddy RS, 102
  • C an ce r T he ra py 2934 Expression of…
  • 2011
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