Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitors

@article{Mo2008ProlongedET,
  title={Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitors},
  author={Irene Fung Ying Mo and Kevin Hak Kong Yip and Wing Keung Chan and Helen K. W. Law and Yu Lung Lau and Godfrey Chi-fung Chan},
  journal={BMC Cell Biology},
  year={2008},
  volume={9},
  pages={52 - 52}
}
Human mesenchymal stromal cells (MSCs, also known as mesenchymal stem cells) are multipotent cells with potential therapeutic value. Owing to their osteogenic capability, MSCs may be clinically applied for facilitating osseointegration in dental implants or orthopedic repair of bony defect. However, whether wound infection or oral microflora may interfere with the growth and osteogenic differentiation of human MSCs remains unknown. This study investigated whether proliferation and osteogenic… CONTINUE READING
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