Prolonged bilateral carotid artery occlusion induces electrophysiological and immunohistochemical changes to the rat retina without causing histological damage.

@article{Barnett1995ProlongedBC,
  title={Prolonged bilateral carotid artery occlusion induces electrophysiological and immunohistochemical changes to the rat retina without causing histological damage.},
  author={Nigel L. Barnett and Neville N Osborne},
  journal={Experimental eye research},
  year={1995},
  volume={61 1},
  pages={83-90}
}
Reduction of the retinal blood flow by occlusion of both common carotid arteries suppressed the b-wave of the rat's electroretinogram. Transient occlusion of the carotids for 45 min reduced the b-wave by 46% without affecting the amplitude of the a-wave. The normal ERG activity returned 30 min after restoration of blood flow. Prolonged carotid occlusion for 7 days totally abolished the b-wave but enhanced the a-wave amplitude. Although b-wave amplitude suppression has been considered as an… CONTINUE READING

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University of Groningen Permanent , bilateral common carotid artery occlusion in the rat

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