Prolonged GIP receptor activation improves cognitive function, hippocampal synaptic plasticity and glucose homeostasis in high-fat fed mice.

Abstract

Enzyme-resistant glucose-dependent insulinotropic polypeptide (GIP) agonists offer therapeutic potential for type 2 diabetes treatment. In addition, there is emerging evidence suggesting that GIP plays a direct role in modulating aspects of brain function. This study compared effects of dietary modification and/or twice-daily injection of the stable GIP… (More)
DOI: 10.1016/j.ejphar.2010.10.059

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Cite this paper

@article{Porter2011ProlongedGR, title={Prolonged GIP receptor activation improves cognitive function, hippocampal synaptic plasticity and glucose homeostasis in high-fat fed mice.}, author={David W Porter and Nigel Irwin and Peter Raymond Flatt and Christian H{\"{o}lscher and V A Gault}, journal={European journal of pharmacology}, year={2011}, volume={650 2-3}, pages={688-93} }