Prolonged E55+ retrovirus expression in aged mice is associated with a decline in the anti-virus immune response.

@article{Elrefaei2001ProlongedER,
  title={Prolonged E55+ retrovirus expression in aged mice is associated with a decline in the anti-virus immune response.},
  author={Mohamed Elrefaei and Kenneth J. Blank and Donna Marie Murasko},
  journal={Virology},
  year={2001},
  volume={290 2},
  pages={281-9}
}
E55+ murine leukemia retrovirus (E55+ MuLV) infection of young and aged C57BL/6 (B6) mice was used to investigate the relationship between increased incidences of infection and decreased immune responsiveness of elderly individuals. Young mice decreased E55+ MuLV burden to below detectable levels by 8 weeks postinfection (p.i.). In contrast, virus burden in… CONTINUE READING