Prolonged Dopamine Signalling in Striatum Signals Proximity and Value of Distant Rewards

@inproceedings{Howe2013ProlongedDS,
  title={Prolonged Dopamine Signalling in Striatum Signals Proximity and Value of Distant Rewards},
  author={Mark W. Howe and Patrick Liam Colm Tierney and Stefan G. Sandberg and Paul E M Phillips and Ann M. Graybiel},
  booktitle={Nature},
  year={2013}
}
Predictions about future rewarding events have a powerful influence on behaviour. The phasic spike activity of dopamine-containing neurons, and corresponding dopamine transients in the striatum, are thought to underlie these predictions, encoding positive and negative reward prediction errors. However, many behaviours are directed towards distant goals, for which transient signals may fail to provide sustained drive. Here we report an extended mode of reward-predictive dopamine signalling in… CONTINUE READING
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