Prolongation of corneal xenotransplant survival by T-cell vaccination-induced T-regulatory cells.


BACKGROUND Corneal xenotransplantation is an alternative approach for overcoming shortage of allograft in clinics. However, the mechanism of acute corneal xenograft rejection and the method of prolonging xenograft survival have not been well defined. METHODS In this study, we used an orthotopic corneal guinea pig-to-rat xenotransplantation model to study… (More)
DOI: 10.1111/j.1399-3089.2008.00471.x