Proline homozygosity in codon 72 of p53: a risk genotype for human papillomavirus related cervical cancer in Indian women.

@article{Bhattacharya2002ProlineHI,
  title={Proline homozygosity in codon 72 of p53: a risk genotype for human papillomavirus related cervical cancer in Indian women.},
  author={Paramita Bhattacharya and Chandralekha Duttagupta and Sharmila Sengupta},
  journal={Cancer letters},
  year={2002},
  volume={188 1-2},
  pages={207-11}
}
The objective of the present study was to determine the codon 72 genotypic frequencies of p53 in Indian women and to analyze the association of this polymorphism with human papillomavirus (HPV) related cervical cancer (CaCx). We used tissues derived from 55 women diagnosed with squamous cell carcinoma of the cervix (of whom 46 were HPV types 16/18 positive) and cervical scrapes derived from 201 cytologically normal women (of whom 84 were HPV types 16/18 positive) as controls. The DNA isolated… CONTINUE READING
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