Proline dehydrogenase: a key enzyme in controlling cellular homeostasis.
@article{Servet2012ProlineDA,
title={Proline dehydrogenase: a key enzyme in controlling cellular homeostasis.},
author={Caroline Servet and Thanos Gh{\'e}lis and Luc Richard and Aviah Zilberstein and Arnould Savour{\'e}},
journal={Frontiers in bioscience},
year={2012},
volume={17},
pages={
607-20
}
}Proline dehydrogenase (ProDH), also called proline oxidase (POX), is a universal enzyme in living organisms. It catalyzes the oxidation of L-proline to delta1-pyrroline-5-carboxylate leading to the release of electrons, which can be transferred to either electron transfer systems or to molecular oxygen. ProDH is not only essential for proline catabolism but also plays key roles in providing energy, shuttling redox potential between cellular compartments and reactive oxygen species production…
77 Citations
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