Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector

@inproceedings{Mantilla2017ProlineMI,
  title={Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector},
  author={Brian Su{\'a}rez Mantilla and Let{\'i}cia Marchese and Aitor Casas-S{\'a}nchez and Naomi A. Dyer and Nicholas Ejeh and Marc Biran and Fr{\'e}d{\'e}ric Bringaud and Michael J. Lehane and {\'A}lvaro Acosta-Serrano and Ariel Mariano Silber},
  booktitle={PLoS pathogens},
  year={2017}
}
Adaptation to different nutritional environments is essential for life cycle completion by all Trypanosoma brucei sub-species. In the tsetse fly vector, L-proline is among the most abundant amino acids and is mainly used by the fly for lactation and to fuel flight muscle. The procyclic (insect) stage of T. b. brucei uses L-proline as its main carbon source… CONTINUE READING