Proliferative potentials of glioma cells and vascular components determined with monoclonal antibody MIB-1.

@article{Di1997ProliferativePO,
  title={Proliferative potentials of glioma cells and vascular components determined with monoclonal antibody MIB-1.},
  author={Xiao-yun Di and Takahumi Nishizaki and Koji Harada and Koichi Kajiwara and Harumi Nakayama and Hisao Ito},
  journal={Journal of experimental & clinical cancer research : CR},
  year={1997},
  volume={16 2},
  pages={153-7}
}
Proliferative activity in 78 glioma specimens was assessed immunohistochemically by determining proliferating index of tumor cells (PTC-PI) and endothelial cells (PEC-PI) using the MIB-1 monoclonal antibody. The PTC-PI of anaplastic astrocytoma (9.0 +/- 5.8: mean + standard deviation) was significantly higher than that of astrocytoma (1.2 +/- 0.4, < 0.01), and lower than that of glioblastoma multiforme (12.0 +/- 5.6, < 0.05). We then compared PTC-PI values with the prognosis of patients with… CONTINUE READING
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