Proliferative hemangiomas: analysis of cytokine gene expression and angiogenesis.

@article{Chang1999ProliferativeHA,
  title={Proliferative hemangiomas: analysis of cytokine gene expression and angiogenesis.},
  author={James Y. C. Chang and Daniel Most and Stephen Bresnick and Babak M Mehrara and Douglas S Steinbrech and John F Reinisch and Michael Thornton Longaker and A E Turk},
  journal={Plastic and reconstructive surgery},
  year={1999},
  volume={103 1},
  pages={1-9; discussion 10}
}
Hemangiomas are benign vascular tumors of childhood that can lead to disfigurement and/or life-threatening consequences. The pathogenesis of hemangioma formation is likely to involve increased angiogenesis. Basic fibroblast growth factor and vascular endothelial growth factor are cytokines that stimulate angiogenesis in multiple in vivo and in vitro models. Proliferative hemangiomas have been found to have elevated levels of basic fibroblast growth factor and vascular endothelial growth factor… CONTINUE READING