Proliferative epithelial lesions of the urinary bladder in cynomolgus monkeys (Macaca fascicularis) infected with Schistosoma intercalatum.

@article{Cheever1976ProliferativeEL,
  title={Proliferative epithelial lesions of the urinary bladder in cynomolgus monkeys (Macaca fascicularis) infected with Schistosoma intercalatum.},
  author={Allen W. Cheever and Robert E. Kuntz and Jon A. Moore and Trevor C. Huang},
  journal={Cancer research},
  year={1976},
  volume={36 8},
  pages={2928-31}
}
Five cynomolgus monkeys (Macaca fascicularis) were infected with Schistosoma intercalatum, a helminth that is morphologically similar to Schistosoma haematobium. Infections were readily established and remained active until the monkeys were sacrificed 21 to 84 weeks after exposure. Although the schistosomes were located predominantly in mesenteric and hepatic portal venules, schistosome eggs were found in the bladders of 3 monkeys. Nodules of atypical epithelial cells interpreted as… CONTINUE READING