Proliferative control in Drosophila stem cells.

@article{Kohlmaier2008ProliferativeCI,
  title={Proliferative control in Drosophila stem cells.},
  author={Alexander Kohlmaier and Bruce A Edgar},
  journal={Current opinion in cell biology},
  year={2008},
  volume={20 6},
  pages={699-706}
}
The relationship between cell growth (cell mass increase over time) and cell division is poorly understood in animal stem cells. Recent studies in several Drosophila stem cell types have provided the tools to interrogate this relationship. In several cases (brat, mei-P26, pros, bam, lethal giant larvae, polo), mutations have been defined that trigger tumorous overproliferation of progenitor cells and reveal how unrestricted self-renewing capacity is controlled. Moreover, microRNAs have been… CONTINUE READING

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