Proliferative characterization of basal-cell carcinoma and trichoepithelioma in small biopsy specimens.

@article{Lum2004ProliferativeCO,
  title={Proliferative characterization of basal-cell carcinoma and trichoepithelioma in small biopsy specimens.},
  author={Christopher A K Lum and Scott Binder},
  journal={Journal of cutaneous pathology},
  year={2004},
  volume={31 8},
  pages={550-4}
}
We examined the proliferative characteristics of 20 basal-cell carcinomas (BCCs) and 16 trichoepitheliomas (TEps) in an effort to understand and explore possible differences in their tumorigenic cell-cycle properties. These tumors were first compared for their expression of the nuclear proliferative protein Ki-67 and the tumor suppressor protein p53. We also compared the p53 downstream effector, p21(waf-1/cip-1), an inhibitor of cyclin-dependent kinases. The other p53-dependent, cyclin… CONTINUE READING
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