Proliferative and cytotoxic effects of mildly oxidized low-density lipoproteins on vascular smooth-muscle cells.

@article{Aug1995ProliferativeAC,
  title={Proliferative and cytotoxic effects of mildly oxidized low-density lipoproteins on vascular smooth-muscle cells.},
  author={Nathalie Aug{\'e} and M. Th. Pieraggi and J. Cl. Thiers and Anne N{\`e}gre-Salvayre and Robert Salvayre},
  journal={The Biochemical journal},
  year={1995},
  volume={309 ( Pt 3)},
  pages={1015-20}
}
We have investigated the role of low-density lipoprotein (LDL) oxidation in the proliferative effect of LDLs on cultured bovine aortic smooth-muscle cells and compared it with their effect on bovine aortic endothelial cells. The following conclusions were reached. (1) Non-toxic doses of mildly oxidized LDLs elicit a proliferative effect on smooth-muscle… CONTINUE READING