Proliferative and cytokine responses to a major surface glycoprotein of Pneumocystis carinii.

@article{Theus1993ProliferativeAC,
  title={Proliferative and cytokine responses to a major surface glycoprotein of Pneumocystis carinii.},
  author={Susan A Theus and Michael Linke and Reagan Andrews and Peter D. Walzer},
  journal={Infection and immunity},
  year={1993},
  volume={61 11},
  pages={4703-9}
}
Naturally derived T-cell responses by rats to a 120-kDa major surface glycoprotein (MSG) of rat-derived Pneumocystis carinii were analyzed in vitro. Specific cytokines elicited by the T-cell response to the MSG were also identified. MSG was purified from rat-derived P. carinii by three different techniques: lectin affinity chromatography, sodium dodecyl sulfate-polyacrylamide gel electrophoresis followed by electroelution, and size-exclusion high-performance liquid chromatography. The cell… CONTINUE READING

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