Proliferative Vitreoretinopathy after Eye Injuries: An Overexpression of Growth Factors and Cytokines Leading to a Retinal Keloid

@inproceedings{Morescalchi2013ProliferativeVA,
  title={Proliferative Vitreoretinopathy after Eye Injuries: An Overexpression of Growth Factors and Cytokines Leading to a Retinal Keloid},
  author={Francesco Morescalchi and Sarah Duse and Elena Gambicorti and Mario R. Romano and Ciro Costagliola and Francesco Semeraro},
  booktitle={Mediators of inflammation},
  year={2013}
}
Eye injury is a significant disabling worldwide health problem. Proliferative Vitreoretinopathy (PVR) is a common complication that develops in up to 40-60% of patients with an open-globe injury. Our knowledge about the pathogenesis of PVR has improved in the last decades. It seems that the introduction of immune cells into the vitreous, like in penetrating ocular trauma, triggers the production of growth factors and cytokines that come in contact with intra-retinal cells, like Müller cells and… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 134 references

Growth factors outside the PDGF family drive experimental PVR.

Investigative ophthalmology & visual science • 2009
View 9 Excerpts
Highly Influenced

PDGF receptors are activated in human epiretinal membranes.

Experimental eye research • 2009
View 4 Excerpts
Highly Influenced

Inhibition of PVR with a tyrosine kinase inhibitor, dasatinib, in the swine.

Investigative ophthalmology & visual science • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…