Proliferation of sorted human and rat beta cells

@article{Parnaud2007ProliferationOS,
  title={Proliferation of sorted human and rat beta cells},
  author={G{\'e}raldine Parnaud and Domenico Bosco and Thierry Berney and François Pattou and Julie Kerr-conte and Marc Yves Donath and Christine Bruun and Thomas Mandrup-Poulsen and Nils Billestrup and Philippe A. Halban},
  journal={Diabetologia},
  year={2007},
  volume={51},
  pages={91-100}
}
The aim of the study was to determine whether purified beta cells can replicate in vitro and whether this is enhanced by extracellular matrix (ECM) and growth factors. Human beta cells were purified by FACS by virtue of their high zinc content using Newport Green, and excluding ductal and dead cells. Rat beta cells were sorted by autofluorescence or using the same method developed for human cells. Cells were plated on poly-l-lysine or ECMs from rat or human bladder carcinoma cells or bovine… CONTINUE READING
BETA

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