Proliferation of rat small hepatocytes after long-term cryopreservation.

@article{Ikeda2002ProliferationOR,
  title={Proliferation of rat small hepatocytes after long-term cryopreservation.},
  author={S. Ikeda and T. Mitaka and K. Harada and S. Sugimoto and K. Hirata and Y. Mochizuki},
  journal={Journal of hepatology},
  year={2002},
  volume={37 1},
  pages={
          7-14
        }
}
BACKGROUND/AIMS The demand for clinical use of hepatocytes is escalating because cell transplantation will be an alternative to orthotopic liver transplantation and the shortage of liver donors is a serious problem throughout the world. However, the supply of fresh differentiated hepatocytes is limited and methods for cryopreservation of hepatocytes that can proliferate with hepatic functions are not satisfactorily established. METHODS Colonies of small hepatocytes were collected and then… Expand
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