Proliferation of ramified microglia on an astrocyte monolayer: characterization of stimulatory and inhibitory cytokines.

@article{Kloss1997ProliferationOR,
  title={Proliferation of ramified microglia on an astrocyte monolayer: characterization of stimulatory and inhibitory cytokines.},
  author={Christian U A Kloss and Georg W. Kreutzberg and Gennadij Raivich},
  journal={Journal of neuroscience research},
  year={1997},
  volume={49 2},
  pages={248-54}
}
Proliferation of ramified microglia is a common phenomenon in brain pathology, but little is known about how this is regulated. In the current study, we examined the effect of different cytokines on the proliferation of ramified microglia in vitro using a combination of autoradiography for [3H]-thymidine and immunocytochemical techniques. Ramified microglia were obtained using a 10-day co-culture on top of a confluent astrocyte monolayer. Addition of macrophage colony-stimulating factor (MCSF… CONTINUE READING

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