Proliferation of bone marrow-derived cells contributes to regeneration after folic acid-induced acute tubular injury.

@article{Fang2005ProliferationOB,
  title={Proliferation of bone marrow-derived cells contributes to regeneration after folic acid-induced acute tubular injury.},
  author={Te-Chao Fang and Malcolm R Alison and H Terence Cook and Rosemary Jeffery and Nicholas Anthony Wright and Richard Poulsom},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2005},
  volume={16 6},
  pages={1723-32}
}
Studies of tissue from recipients of bone marrow transplantation or organ allograft suggest that bone marrow-derived cells (BMDC) may differentiate into a variety of nonhematologic tissues, including renal tubular epithelium. The aims of this study were to examine whether BMDC contribute to recovery after acute renal injury and to assess the effects of cytokine mobilization on regeneration. Female mice (6 wk old) were lethally irradiated and transplanted with male bone marrow (BM) cells and… CONTINUE READING
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  • R Safirstein, PM Price, SJ Saggi, RC Harris
  • J Am Soc Nephrol
  • 2005
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