Proliferation-dependent and cell cycle–regulated transcription of mouse pericentric heterochromatin

@article{Lu2007ProliferationdependentAC,
  title={Proliferation-dependent and cell cycle–regulated transcription of mouse pericentric heterochromatin},
  author={Junjie Lu and David M. Gilbert},
  journal={The Journal of Cell Biology},
  year={2007},
  volume={179},
  pages={411 - 421}
}
Pericentric heterochromatin transcription has been implicated in Schizosaccharomyces pombe heterochromatin assembly and maintenance. However, in mammalian systems, evidence for such transcription is inconsistent. We identify two populations of RNA polymerase II-dependent mouse gamma satellite repeat sequence-derived transcripts from pericentric heterochromatin that accumulate at different times during the cell cycle. A small RNA species was synthesized exclusively during mitosis and rapidly… CONTINUE READING
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