Proliferation and apoptotic rates and increased frequency of p63-positive cells in the prostate acinar epithelium of alloxan-induced diabetic rats.

@article{Arcolino2010ProliferationAA,
  title={Proliferation and apoptotic rates and increased frequency of p63-positive cells in the prostate acinar epithelium of alloxan-induced diabetic rats.},
  author={Fanny Oliveira Arcolino and Daniele L Ribeiro and Marina Guimar{\~a}es Gobbo and Sebasti{\~a}o R Taboga and Rejane M G{\'o}es},
  journal={International journal of experimental pathology},
  year={2010},
  volume={91 2},
  pages={144-54}
}
The effects of experimental type 1 diabetes were investigated in the acinar epithelium of rat ventral prostate, focusing on the rates of cell proliferation and the frequency of apoptosis and p63-positive cells. Type 1 diabetes was induced in adult male Wistar rats by a single alloxan administration (42 mg/kg b.w.) and its effects were analysed for 1 week and 3 months after the establishment of the disease. A group of diabetic rats was treated daily with 5 IU of insulin during 1 week after… CONTINUE READING

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