Proliferation, migration, and differentiation of human neural stem/progenitor cells after transplantation into a rat model of traumatic brain injury.

@article{Wennersten2004ProliferationMA,
  title={Proliferation, migration, and differentiation of human neural stem/progenitor cells after transplantation into a rat model of traumatic brain injury.},
  author={Andr{\'e} Wennersten and Xia Meier and Staffan Holmin and Lars U. Wahlberg and Tiit Mathiesen},
  journal={Journal of neurosurgery},
  year={2004},
  volume={100 1},
  pages={88-96}
}
OBJECT Cultures containing human neural stem and progenitor cells (neurospheres) have the capacity to proliferate and differentiate into the major phenotypes of the adult brain. These properties make them candidates for therapeutic transplantation in cases of neurological diseases that involve cell loss. In this study, long-term cultured and cryopreserved cells were transplanted into the traumatically injured rat brain to evaluate the potential for human neural stem/progenitor cells to survive… CONTINUE READING

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