Proliferating endothelial cells, but not microvessel density, are a prognostic parameter in human cutaneous melanoma.

Abstract

The induction of angiogenesis is crucial in the development of most human tumors. Angiogenesis is routinely assessed by the density of tumor microvessels. This technique reveals controversial results on the clinical and prognostic value of angiogenesis in melanoma. We investigated angiogenesis in tumor tissues of 58 cutaneous melanoma patients, of which a… (More)

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