Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota.

Abstract

Y-family DNA polymerases are believed to facilitate the replicative bypass of damaged DNA in a process commonly referred to as translesion synthesis. With the exception of DNA polymerase eta (poleta), which is defective in humans with the Xeroderma pigmentosum variant (XP-V) phenotype, little is known about the cellular function(s) of the remaining human Y… (More)

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@article{Vidal2004ProliferatingCN, title={Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota.}, author={Antonio E. Vidal and Patricia L. Kannouche and Vladimir N. Podust and Wei Yang and A. R. Lehmann and Roger Woodgate}, journal={The Journal of biological chemistry}, year={2004}, volume={279 46}, pages={48360-8} }