Proliferating cell nuclear antigen (PCNA) as a marker of dysplasia in oral mucosa.

@article{MartnezLara1996ProliferatingCN,
  title={Proliferating cell nuclear antigen (PCNA) as a marker of dysplasia in oral mucosa.},
  author={I Mart{\'i}nez-Lara and Miguel {\'A}ngel Gonz{\'a}lez-Moles and Isabel Ruiz-{\'A}vila and Milagros Bravo and Mar{\'i}a Cristina Fern{\'a}ndez Ramos and J A Fern{\'a}ndez-Mart{\'i}nez},
  journal={Acta stomatologica Belgica},
  year={1996},
  volume={93 1},
  pages={
          29-32
        }
}
The development of head and neck cancer has been proposed to be a multistep process, with accumulation of genetic and phenotypic alterations resulting from carcinogen exposure. Proliferating cell nuclear antigen (PCNA), also called cyclin, is a 36-KD auxiliary protein of DNA polymerase-delta, that has been found to be a useful marker in immunocytochemical studies of cell proliferation because its expression correlates with the proliferative state of the cell. PCNA expression was analyzed in 10… CONTINUE READING

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