Proliferating cell nuclear antigen (PCNA) immunolabeling as a prognostic factor in axillary lymph node negative breast cancer.

@article{Aaltomaa1993ProliferatingCN,
  title={Proliferating cell nuclear antigen (PCNA) immunolabeling as a prognostic factor in axillary lymph node negative breast cancer.},
  author={Sirpa H Aaltomaa and Pertti K. Lipponen and Kari Juhani Syrj{\"a}nen},
  journal={Anticancer research},
  year={1993},
  volume={13 2},
  pages={533-8}
}
The fraction of nuclei positive for proliferating cell nuclear antigen (PCNA) was determined in 205 axillary lymph node negative (pN-) breast carcinoma. The results were related to established prognostic factors and prognosis during the mean follow-up period of 11 years. The maximum fraction of PCNA-positive nuclei (PCNAmax), the average fraction of positive nuclei (PCNAtot) and the number of intensively stained nuclei/microscope field (PCNAcount) were significantly related to histological… CONTINUE READING
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